80,000 Hours Podcast With Rob Wiblin

Back in 2007, Holden Karnofsky cofounded GiveWell, where he sought out the charities that most cost-effectively helped save lives. He then cofounded Open Philanthropy, where he oversaw a team making billions of dollars’ worth of grants across a range of areas: pandemic control, criminal justice reform, farmed animal welfare, and making AI safe, among others. This year, having learned about AI for years and observed recent events, he's narrowing his focus once again, this time on making the transition to advanced AI go well.In today's conversation, Holden returns to the show to share his overall understanding of the promise and the risks posed by machine intelligence, and what to do about it. That understanding has accumulated over around 14 years, during which he went from being sceptical that AI was important or risky, to making AI risks the focus of his work.Links to learn more, summary and full transcript.(As Holden reminds us, his wife is also the president of one of the world's top AI labs, Anthropic, gi