NIEHS Superfund Research Program - Research Brief Podcasts
TBT Alters Bone Marrow Microenvironment and Suppresses Important Immune Cells
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Sinopsis
Researchers at the Boston University Superfund Research Program (BU SRP) Center reported that tributyltin (TBT) may promote aging-related problems in immune health. The team, led by Jennifer Schlezinger, Ph.D., found that TBT impacts bone marrow B cells directly by triggering cell death and indirectly by changing the microenvironment of bone marrow vital for supporting immune health.