American Journal Of Psychiatry Audio

This audio program includes a discussion of a study that used an algorithm to search electronic health records for clinical information relevant to the Research Domain Criteria; an article on predicting the transition from mild cognitive impairment to dementia; a trial on reducing reactivity to alcohol cues in patients with alcohol dependence; a study of the relationship between C-reactive protein and symptoms of PTSD; a trial examining the influences of health coaching for overweight persons with serious mental illness; and an intriguing short essay about correspondence between Charles Darwin and the head gardener at an English mental institution. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of adjustment disorder in a health care worker with Ebola, a case of psychotic symptoms that improved with a gluten-free diet, medication prescribing for first-episode schizophrenia, outcomes for young people at ultra-high risk for psychosis who do not transition to psychotic disorders, possible mechanisms in perimenopausal depression, and change during adolescence in reactivity of the amygdala in relation to stressful life events and family history of depression. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a study of postpartum psychosis and mania, a home-visiting intervention for pregnant teenage American Indian mothers, brain patterns underlying learning deficits in autism spectrum disorders, the clusters of genetic variants and clinical features of schizophrenia, the Affordable Care Act and its expansion of insurance for young adults. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of hypercalcemia and hyperparathyroidism during lithium therapy. It also examines ECT for treatment-resistant bipolar depression and for clozapine-resistant schizophrenia; a weight loss intervention for individuals taking antipsychotic medications; an intervention for kindergartners with chronic conduct problems; a clinical trial offering depression care in OB-GYN clinics; and treatment response related to insurance. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of mercury poisoning and its neuropsychiatric presentations and presents a large study that used a new approach to testing the effect of antidepressants on heart rate. Several articles are about biomarkers of psychiatric illness: one identified a combined epigenetic and genetic biomarker for suicide, and another found that a measure of inflammation in depressed patients predicted the outcome of treatment with escitalopram and nortriptyline. Finally, a commentary on biomarkers considers how biological tests can be incorporated into psychiatric diagnostic criteria. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program explores pulmonary embolism in psychiatric patients, a trial of smoking cessation combining varenicline and bupropion, a trial comparing quetiapine with placebo for treatment of borderline personality disorder, a study of positive traits in co-twins of patients with bipolar disorder, a study evaluating the genetic and environmental contributions to familial recurrence of autism spectrum disorder, and a long-term study of the effectiveness of supported employment for persons with severe mental illness. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program explores relapse prevention in pediatric depression and the risk of mania or hypomania for patients with bipolar depression taking an antidepressant without a mood stabilizer. The series on global mental health describes a man in Cambodia with seizures, anorexia, and depression. The issue covers adverse neuropsychiatric effects of glucocorticoid medications, the patient-therapist relationship in psychotherapy, and the outcomes of psychodynamic therapy and CBT in social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents diagnostic and treatment aspects of disruptive mood dysregulation disorder, predictors of long-term outcome in youths with bipolar disorder, reading ability and elements of impulsivity related to aggression in schizophrenia, a global health review of a woman in Uganda with HIV and major depression, and the connection between schizophrenia and maternal levels of C-reactive protein. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents a case of delirium with manic symptoms in a patient with end-stage COPD, a clinical vignette about a chronically depressed woman in Iran, low dopamine transmission in the prefrontal cortex of people with alcoholism, a test of mindfulness training as a way to increase resilience in Marines before deployment, the influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in the offspring of Holocaust survivors, and the ties between the unexpected death of a loved one and psychiatric disorders across the life span. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a new tool for screening military veterans to evaluate the risk of violence. One article reviews the care of pregnant women with ADHD, and another one reports on outcomes after in-utero exposure to lithium. Also discussed is the treatment of separation, generalized, and social anxiety disorders in children and adolescents, and two longitudinal studies shed light on the continuity of preschool depression and on adult health and functioning in people who were bullied as children. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses DSM-5 classification of anxiety and related disorders, antipsychotic use in breast cancer patients, and adult outcomes of disruptive mood dysregulation disorder. Treatment trials for a parental intervention aimed at preventing antisocial personality and family-focused treatment plus medication for adolescents with bipolar disorder are also examined. The issue also looks at Internet-delivered treatment for substance abuse, virtual reality therapy for PTSD in conjunction with either D-cycloserine or alprazolam, and treatment with a synthetic neuro-active steroid via aerosol nasal spray for women with social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program begins with a new section, Perspectives in Global Mental Health, featuring cultural aspects of depression and ideas for global dissemination of psychological treatments. The issue also examines psychological interventions for psychosis, cognitive training, dietary coaching for elderly persons with subsyndromal depressive symptoms, psychiatric symptoms as risk factors for mild cognitive impairment, and how brain development relates to depression onset. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program offers a commentary on the Research Domain Criteria project by the Director of NIMH. In addition, it reviews liver injury due to antidepressants, head injury as a risk factor for psychiatric disorders, whether women and men differ in the etiology of depression, the effect of cannabis on working memory in adolescent monkeys, whether a genetic polymorphism affected topiramate’s efficacy for reducing alcohol consumption, and a clinical trial of computer-assisted cognitive-behavioral therapy for cocaine-dependent individuals maintained with methadone. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines lurasidone treatment of bipolar depression, both as monotherapy and as an adjunct; psychotherapy for bipolar depression related to comorbid anxiety disorders; a computerized method for rating anxiety; genetic, family, and community risk factors for drug abuse; the risk of autoimmune diseases in individuals with a personal or family history of schizophrenia or related psychosis; and how memory is affected by knowing whether one has a gene variant that increases the risk for Alzheimer’s disease. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines the risk of upper gastrointestinal bleeding with short-term use of SSRIs and schizophrenia complicated by hepatitis C and hepatic encephalopathy. It also reports results from a study in which neuropsychological functioning was tracked from childhood to age 38, a study comparing psychoanalytic psychotherapy and CBT for bulimia nervosa, a review of the relation of childhood separation anxiety to adult anxiety disorders, and a review comparing approaches to refractory social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program includes a case of folie à deux and infanticide, the DSM-5 changes in sleep disorder classification, and new research on ketamine for treatment-resistant depression. Two reports explore brain structure and functioning in patients with eating disorders. Additional studies examine neural mechanisms of frustration in chronically irritable children and the role of oxytocin in mental illness and its treatment. One study looked at the effect of oxytocin on social threat hypersensitivity in women with borderline personality disorder. Another one analyzed how oxytocin moderates the relationship between maternal depression and child mental health. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines relationships between violence and mental illness. This issue looks at psychiatric characteristics of homicide defendants, differences in mental illness between gang members and other men with violent behavior, and aggression in a child with Asperger’s disorder. It also features a study of the relationship between firearms availability and suicide risk, a trial of prazosin for treatment of nightmares in combat-related PTSD, a study comparing cognitive-behavioral therapy and short-term psychodynamic therapy for depression, and a long-term study on the effects of antipsychotics in Alzheimer’s disease. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains articles on the behavioral treatment of insomnia in bipolar disorder, the relation of childhood trauma to psychotic experiences, comparing psychodynamic therapy and cognitive-behavioral therapy (CBT) for social anxiety disorder, augmenting antidepressant treatment with CBT for generalized anxiety disorder in older adults, and late-onset agoraphobia in a population study that identified new cases of agoraphobia over 4 years in the elderly. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains several articles on the treatment of depression. It examines brain tissue loss in schizophrenia and brain changes in women with childhood histories of sexual and emotional abuse. One perspective article details how advanced paternal age could contribute to neurodevelopmental disorders, a commentary describes the DSM-5 section on neurocognitive disorders, and the Treatment in Psychiatry article describes how to handle psychiatric issues related to interferon treatment. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains research that considers clozapine as a first-line treatment for schizophrenia, a recently developed scale for negative symptoms, the new DSM-5 diagnosis disruptive mood dysregulation disorder, the effects of mental health parity in the Federal Employees Health Benefits Program, and a surprising finding on successful aging. Articles can be viewed online at www.ajp.psychiatryonline.org.