Corconsult Rx: Evidence-based Medicine And Pharmacy

On this episode, we review the 2023 Hepatitis C Guidance that was recently published by the Infectious Diseases Society of America (IDSA) and the American Association for the Study of Liver Diseases (AASLD). We discuss the pre-treatment work-up, various treatment options, and drug-drug interactions/clinical pearls for the most commonly used direct-acting antivirals.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re no

On this episode, Cole and I review some of the medications that gained U.S. FDA approval in 2023. We cover a variety of medications that treat various disease states. We focused more on outpatient medications and did not cover new oncology medication approvals.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membersh

On this episode, my good friend and colleague Alex Hovey, PA-C is sitting in for Cole this episode. We review the treatment of acute rhinosinusitis and pharyngitis. We mention some treatment options for symptom relief in patients with viral sinusitis and viral pharyngitis. We spend the majority of the episode covering the treatment algorithm for bacterial sinusitis and pharyngitis. We also used this episode to review some antibiotic clinical pearls.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the

On this episode we review post-traumatic stress disorder (PTSD). We discuss some background information on the disease. Then, we review the various treatment options used to manage PTSD symptoms. To finish the episode, we go through Dr. David N. Osser, MD's PTSD treatment algorithm.  Dr. David N. Osser, MD is associate professor of psychiatry at Harvard Medical School at the Brockton Division of the VA Boston Health System.  There, he is the Medical Director for Domiciliary Care for Homeless Veterans and general editor of the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program. You can see his PTSD algorithm and others at the website below: Osser Psychopharmacology Algorithms Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes.

On this episode, we discuss the 5-HT1A receptor agonist, Exxua (gepirone). Exxua was recently FDA approved for the treatment of general depression. We review the long road this medication took to get approved. We also summarize the dosing, adverse effects, drug-drug interactions, etc for Exxua.  Thanks for listening! We want to give a big thanks to our sponsor, High-Powered Medicine. HPM is a book/website database of summaries for over 150 landmark clinical trials. You can get a copy of HPM, written by Dr. Alex Poppen, PharmD, at the links below:  Purchase a subscription or PDF copy - https://highpoweredmedicine.com/ Purchase the paperback and hardcover - Barnes and Noble website We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial: www.pyrls.com/corconsultrx If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable

On this episode, we review the management of chronic kidney disease. We discuss when to use iron vs erythropoietin-stimulating agents (ESAs) for a patient with anemia due to their CKD.  We also go over the management of metabolic acidosis, hyperphosphatemia, secondary hyperparathyroidism, etc.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the ben

On this episode we discuss the management of benign prostatic hyperplasia (BPH) as well as overactive bladder (OAB). We review alpha blockers, 5-alpha-reductase inhihibitors, PDE5-inhibitors, anticholinergics, and beta 3 agonists. We close by discussing the best treatment options for patients with controlled BPH symptoms who are still experiencing urinary frequency and urgency.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/

On this episode, we review the treatment of both uncomplicated and complicated urinary tract infections (UTIs). We also use this episode to refresh some clinical pearls for the various antibiotics that are used when treating a UTI.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn C

On this episdoe, we are joined by Dr. Alex Poppen, PharmD, the author of High Powered Medicine. HPM is a book that summarizes over 150 landmark clinical trials. We discuss how Alex came up with the idea for the book as well as how he got it published. We finish the episode with a quick review of the LoDoCo2 trial looking at colchicine for CV risk reduction.  To purchase either the digital or the hardcopy version of High Powered Medicine, check out the links below: Link to official HPM website (where you can purchase a subscription or PDF copy, or just create an account and download a free sample)   Link to Barnes and Noble website where you can buy the paperback version   Thanks for listening! We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial: www.pyrls.com/corconsultrx If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as we

On this episode, we discuss both treating an acute gout flare and chronic management of gout. We discuss colchicine, NSAIDS, corticosteroids, canakinumab, xanthine oxidase inhibitors, uricosurics, URAT-1 inhibitor, and more.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for l

On this episode, we review pharmacotherapy options for managing osteoarthritis pain. We focus primarily on on hand, knee, and hip OA. We cover NSAIDS, COX2 inhibitors, topical capsaicin, intra-articular corticosteroids, intra-articular hyaluronic acid, duloxetine, and more.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlim

On this episode, we review the medications that are FDA approved for weight loss. We also review recent data on high dose oral semaglutide and injectable tirzepatide. We end by looking at drugs that are currently in the pipeline with unique mechanisms of action.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Members

On this episode, we are joined by Dr. Brian Gilbert, PharmD, BCCCP, FCCM, FNCS, to compare and contrast alteplase (tPA) versus tenecteplase (TNK-tPA) in the setting ischemic stroke. Brian is an emergency medicine clinical pharmacy specialist at Wesley Medical Center. He also serves as the PGY-2 critical care pharmacy residency program director and as an adjunct assistant clinical professor at the University of Kansas School of Pharmacy.  Thanks for listening! We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial: www.pyrls.com/corconsultrx If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - 

On this episode, we review the management of hypothyroidism. We focus on levothyroxine as the foundation for a patient treatment. We also discuss the contraversial issue of using synthetic T3 (liothyronine) as an augmentation option for certain patients. The link to the Medscape article, Why the Hesitancy in Recommending Combination T3/T4 Therapy with Dr. Kaniksha Desai, MD and Dr. Antonio Bianco, MD, PhD, is available below:  Why the Hesitancy in Recommending Combination T3/T4 Therapy? Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To ea

On this episode, we discuss the various treatment options for community acquired pneumonia. We compare and contrast the differences in treating a patient with and without comorbidities in the outpatient setting as well as non-severe and severe CAP in the inpatient setting. We also review some basics for the various antibiotics used in CAP. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member,

On this episode, we discuss the management of substance use disorder. We review the pharmacotherapy/psychotherapy options for treating the abuse of alcohol, cocaine, methamphetamine, cannabis, benzodiazepines, and opioids. Make sure to check out our previous episode that covers opioid use disorder specifically.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we definitely suggest you e

On this episode, we discuss the pharmacotherapy options available for smoking cessation. We start with some background info including pathophysiology, psychology models applicable to smoking cessation, and nicotine dependence assessments.  We review varenicline, nicotine replacement therapy in various forms, bupropion SR, and others.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you’re not currently a freeCE member, we d

On this episode, we go over a pharmacotherapy plan for a patient with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and OSA. Episode 227 Patient Case Information 57-year-old male with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and OSA comes to your clinic to establish care. His primary concern is the number of sickle cell crisis he has been experiencing (3 ER visits in the last 5 months). He is having significant constipation daily due to his maintenance opioid regimen.  He also reports difficulty controlling his blood glucose. He has experienced 6 hypoglycemic events (BG range between 65 and as low as 42) and is confused as to what he is doing wrong with managing his diabetes. He is also concerned because he is having vivid nightmares almost every night. He also asks about the best artificial tears to get OTC because his Refresh Optive (carboxymethylcellulose) doesn’t seem to be working any

On this episode, we discuss the considerations and possible changes to a patient's general depression regimen when they have various comorbidities or other circumstances that affect their health . The comorbidities/situations that we cover include: patients with coronary artery disease, patients over the age of 65, patients that are pregnant, chronic pain, OCD, ADHD, PTSD, and more. We also review depression with atypical features, depression with mixed features, and depression with anxious distress.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activ

On this episode, we discuss Vowst, the oral fecal microbiota product for preventing the recurrance of C. diff infection. We review Vowst's dosing, administration, drug-drug interactions, clinical trial data, and more.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx