Questioning Medicine

41 adults (mean age, 59) with obesity (mean weight, 99 kg) and prediabetes or diet-controlled diabetes – everyone got the same diet. Same  micro- and macronutrient composition; same calorie amounts Food was prepared in a study kitchen and consumed onsite or taken home.Key differenceThe intervention group was instructed to eat between 8 a.m. and 6 p.m. and to consume 80% of calories by 1 p.m. The control group was instructed to eat between 8 a.m. and midnight, with 55% of calories after 5 p.m.Weight loss in the two groups was similar at 12 weeks (about 2.4 kg).3 months—and no difference—https://www.acpjournals.org/doi/10.7326/M23-3132