Sinopsis
Are you searching for stories to ignite your curiosity, teach you to perform better in life and career, inspire your mind, and make you laugh along the way? In this science podcast, Dr. Marie McNeely introduces you to the brilliant researchers behind the latest discoveries in science. Join us as they share their greatest failures, most staggering successes, candid career advice, and what drives them forward in life and science.
Episodios
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524: Researching How Plant Cells Sense and Respond to Internal Forces - Dr. Elizabeth Haswell
21/10/2019 Duración: 41minDr. Elizabeth Haswell is a Professor of Biology at Washington University in St. Louis and a Howard Hughes Medical Institute (HHMI)-Simons Faculty Scholar. Liz’s research examines how the molecules, cells, and tissues within plants can sense and respond to forces. In particular, she studies a type of proteins that is really sensitive to mechanical signals called mechanosensitive ion channels. Liz is working to understand how these mechanosensitive ion channels sense and respond to internal forces within plant cells, such as turgor pressure (i.e. the water pressure within cells). In her free time, Liz enjoys traveling, hiking, hanging out with her family, and reading. She also co-hosts a plant biology podcast called The Taproot. She received her B.S. degree in biochemistry from the University of Washington and her Ph.D. in biochemistry from the University of California, San Francisco. Afterwards, Liz conducted postdoctoral research at the California Institute of Technology before joining the faculty at Washingt
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523: Physicist Figuring Out How Materials Deform and Fail - Dr. Karen Daniels
14/10/2019 Duración: 40minDr. Karen Daniels is a Professor in the Department of Physics at North Carolina State University. Karen’s lab investigates the physics of how materials change state (e.g. from solid to fluid), how they deform, and how they may ultimately fail. She studies these questions across a variety of length and time scales, from microscopic phenomena that occur in less than a second to shifts in land that occur on geologic timescales and may lead to landslides. Travel is a passion for Karen. While traveling, she loves hiking on mountain trails, eating delicious food, discovering new foods that she can try to make at home, reading books, knitting, and interacting with new people and places. She received her BA in physics from Dartmouth College. Karen then worked for about three years as a science teacher at Saint Ann’s School in Brooklyn before enrolling in graduate school at Cornell University where she earned her PhD in physics. She then conducted postdoctoral research at Duke University before joining the faculty at
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522: Generating Genomic Therapies to Treat Huntington's Disease and Other Conditions - Dr. Edward Rebar
07/10/2019 Duración: 30minDr. Edward Rebar is Senior Vice President and Chief Technology Officer at Sangamo Therapeutics. Ed and the team at Sangamo are developing genomic medicines. They use different techniques including gene therapy, ex vivo genome editing (using cells sourced from outside the body), in vivo genome editing (using a patient’s own cells within their body), and in vivo targeted gene regulation to downregulate their genes of interest. When Ed isn’t at work, he loves being outside with his wife, going to local parks, and visiting National Parks. When walking around observing nature, he tries to understand the story behind what he sees. He particularly enjoys exploring and pondering the amazing rock formations in Southern Utah. Ed earned his B.S. degree in biochemistry from Rutgers University and his Ph.D. in biophysics and structural biology from MIT. He conducted postdoctoral research at the University of California, Berkeley before joining the team at Sangamo in 1998. In our interview, Ed shares more about his life an
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521: Examining the Role of Epigenomics in Development and Disease - Dr. Joyce Ohm
30/09/2019 Duración: 42min -
520: Deciphering Genome Differences Associated with Diseases Like ALS - Dr. Molly Gale Hammell
23/09/2019 Duración: 32min -
519: Exploring Causes, Degenerative Mechanisms, and Potential Therapies for Parkinson's Disease - Dr. Kim Tieu
16/09/2019 Duración: 39minDr. Kim Tieu is Professor and Interim Chair in the Department of Environmental Health Sciences in the Robert Stempel College of Public Health & Social Work at Florida International University. Kim’s research focuses on three related areas. The first is understanding why people develop Parkinson’s disease (PD). The genetic or environmental causes of PD are unknown in about 90% of cases. Kim is studying the effects of environmental toxins on the development and progression of PD. The second major area of research in Kim’s lab examines why and how the dopamine-producing neurons die in a part of the brain called the basal ganglia in people with PD. A third research line in Kim’s lab aims to develop an effective drug therapy for PD. Kim loves going to the beach to swim, snorkel, and fish with his family. He also enjoys travel, photography, yard work, and tending to his approximately 30 fruit trees. He received his bachelor’s degree in pharmacy from the University of Saskatchewan and subsequently worked as a ph
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518: Examining Emotions and How They Affect Our Actions - Dr. Jessica Tracy
09/09/2019 Duración: 42minDr. Jessica Tracy is a Professor in the Department of Psychology and Director of the Emotion and Self Laboratory at the University of British Columbia. In addition, she is a University of British Columbia Sauder School of Business Distinguished Scholar and author of the book Take Pride: Why the Deadliest Sin Holds the Secret to Human Success. Jess conducts research in the field of social and personality psychology. Her lab focuses on better understanding the self-conscious emotions we feel when we are evaluating ourselves. Some examples of self-conscious emotions are pride and shame. In her free time, Jess enjoys being outdoors in beautiful Vancouver, British Columbia. Some of her favorite outdoor activities are hiking, running, visiting the beach, and skiing. Jess received her B.A. in psychology From Amherst College, and she was awarded her M.A. and PhD in social-personality psychology from the University of California, Davis. After a brief postdoctoral fellowship at the University of California, Davis, Jess
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517: Investigating How Insects Transmit Plant Pathogens And How To Prevent Propagation - Dr. Michelle Heck
02/09/2019 Duración: 39minDr. Michelle Heck is a Research Molecular Biologist with the U.S. Department of Agriculture (USDA) Agricultural Research Service (ARS), an Associate Professor at the Boyce Thompson Institute for Plant Research, as well as an Adjunct Professor in the school of Integrative Plant Science at Cornell University. Michelle studies interactions between the insects that infest plants, the pathogens that those insects can transmit, the diseases that can occur as a result, and new ways to control the spread of these diseases. Outside the lab, she loves spending time with her fantastic family, being a musician, watching her kids get interested in music, and cycling in scenic areas nearby. Michelle received her B.A. degree in biology from Boston University and her Ph.D. in biology from Watson School of Biological Sciences at Cold Spring Harbor Laboratory. She then conducted postdoctoral research at Cornell University. Michell has received numerous awards and honors throughout her career, including the 2014 USDA ARS Herber
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516: Dedicated to Clinical Care and Conducting Research to Combat Childhood Cancers - Dr. Uri Tabori
26/08/2019 Duración: 37minDr. Uri Tabori is a Staff Physician in the Division of Haematology/Oncology, Senior Scientist in the Genetics & Genome Biology program, and Principal Investigator of The Arthur and Sonia Labatt Brain Tumour Research Centre at The Hospital for Sick Children (SickKids). In addition, Uri is a Professor in Paediatrics and Associate Professor in the Institute of Medical Sciences at the University of Toronto. Uri works as a physician treating kids with cancer, particularly brain tumors. Through his research, he is working to identify drugs and make new discoveries that may cure cancers or improve patients’ lives. When he’s not hard at work in the lab or clinic, Uri enjoys spending time with his family, watching American football, and exploring the wilderness of Canada. In particular, he is fond of canoeing and canoe camping with his family. He received his MD from the Hadassah School of Medicine of Hebrew University in Israel. Afterwards, he completed a Rotating Internship and his Residency in Pediatrics at the
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515: Studying Young Stars to Shed Light on Planet Formation - Dr. Meredith Hughes
19/08/2019 Duración: 41minDr. Meredith Hughes is an Associate Professor of Astronomy at Wesleyan University. In her research, Meredith uses large radio telescopes to study how planets form around other stars. After stars are formed, disks of leftover gas and dust go on to form planets. Meredith studies how this process works, the conditions that exist in these early disks, how the disks form planets, and the types of planets that form around stars. Studying this process in other star systems helps us learn more about our own solar system and how it formed.When Meredith isn’t working, you can find her hanging out with her husband, two young kids, and their dog. She also enjoys reading fantasy and sci-fi books, being outdoors, and volunteering in her community. She received her B.S. degree in Physics & Astronomy from Yale University. Afterwards, Meredith attended graduate school at Harvard University where she received her M.A. and Ph.D. degrees in Astronomy. She was awarded a Miller Fellowship to conduct postdoctoral research in th
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514: Examining the Effects of Environmental Stress on Fish and Aquatic Invertebrates - Dr. Susanne Brander
12/08/2019 Duración: 43minDr. Susanne Brander is an Assistant Professor in the Department of Environmental and Molecular Toxicology at Oregon State University. Susanne is an ecotoxicologist who studies the effects of environmental stress on wildlife. She particularly focuses on aquatic organisms that live in coastal areas, estuaries, and marine environments. Her research examines how environmental stressors affect organisms’ ability to function, reproduce, grow, and survive. In addition, Susanne assesses the risk of chemicals like pesticides or pharmaceuticals in waste waters in terms of how they might affect the health and survival of fish and other invertebrates. In her free time, Susanne enjoys hanging out with her two young daughters, hiking, and doing art and science projects at home with them. She also likes running and making bowls and coffee cups on her pottery wheel. Susanne received her B.S. degree in Business Administration from Elizabethtown College, her M.S. degree in Environmental Science and Policy from Johns Hopkins Un
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513: Dr. Nick Haddad: Recovering Rare and Endangered Butterfly Populations through Conservation Corridors and Other Strategies
05/08/2019 Duración: 59minDr. Nick Haddad is a Professor in Integrative Biology at Michigan State University and a Senior Terrestrial Ecologist at the W.K. Kellogg Biological Station. In addition, Nick is the author of the recently released book The Last Butterflies: A Scientist's Quest to Save a Rare and Vanishing Creature. Through his research, Nick searches for the rarest butterflies in the world and works to understand what factors cause the decline of these butterflies and what we can do to conserve them. Outside of work, Nick has been enjoying renovating his home with his wife who is a historic preservationist. Their home was built in 1840, so they have been tackling a wide variety of projects including updating the plumbing and replacing all of the electrical wiring. Nick received his BS in Biology from Stanford University, and he was awarded his PhD in Ecology from the University of Georgia. Afterwards, Nick conducted postdoctoral research at the University of Minnesota. Before joining the faculty at Michigan State, University
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512: Developing New Cancer Treatments Using T Cell Receptor-Based Biologics - Dr. David Berman
29/07/2019 Duración: 42minDr. David Berman is Head of Research and Development at Immunocore, a leading T cell receptor biotechnology company. David and his team are working on new therapies that can train the immune system to recognize and kill cancer. This approach to treating cancer is called immunotherapy. Immunocore is taking a novel approach to immunotherapy by leveraging the mechanisms used by T cell receptors to identify indicators of cancer within cancer cells. Much of David’s time outside of work is spent driving his daughters to their soccer and lacrosse games and watching them play. He also enjoys cycling with his family and thought-provoking solo cycling outings. He received his bachelor’s degree in biology from the Massachusetts Institute of Technology. Afterwards, David was awarded his PhD under the mentorship of Dr. Alfred Gilman (Nobel Prize 1994) and his MD from the University of Texas Southwestern Medical Center at Dallas. He completed his Residency in Anatomic Pathology at the National Cancer Institute and a Fellow
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511: Getting Straight to the Point Studying the Shape and Function of Shark Teeth - Dr. Lisa Whitenack
22/07/2019 Duración: 41minDr. Lisa Whitenack is an Associate Professor in the Departments of Biology and Geology at Allegheny College. Through her research, Lisa aims to better understand how animals work from a mechanical perspective. She studies how sharks have used their teeth over their 400 million years of evolution, how salamanders jump, and how stone crabs perform pinching movements. When she’s not at work, Lisa loves getting creative with a variety of crafts such as crochet, cross-stitch, and painting. She also enjoys refereeing roller derby, hiking, and spending time with her family. Lisa received her B.S. in geology from the University of Illinois at Urbana-Champaign, her M.S. degree in geological sciences from Michigan State University, and her Ph.D. in integrative biology from the University of South Florida. Lisa served as an adjunct faculty member at the University of Tampa for about a year. She next conducted postdoctoral research in geology at the University of South Florida before joining the faculty at Allegheny Coll
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510: Creating New Compounds to Treat Central Nervous System Disorders - Dr. Al Robichaud
15/07/2019 Duración: 37minDr. Al Robichaud is Chief Scientific Officer at Sage Therapeutics, a clinical-stage biopharmaceutical company committed to developing and commercializing novel medicines to treat life-altering central nervous system disorders. The team at Sage Therapeutics is focused on delivering new medicines for people with central nervous system disorders, such as depression. The compounds they have developed modulate the activity of receptors in the brain that respond to specific neurotransmitters. Outside of science, Al has been an avid scuba diver for most of his life. He particularly enjoys exploring the ocean in the Caribbean with his family. Al received his B.S. in chemistry from Rensselaer Polytechnic Institute. He worked as a staff chemist at FMC Corporation for about two years before returning to school to earn his PhD in Organic Chemistry from the University of California, Irvine. Al next conducted research as an American Cancer Society postdoctoral fellow in organic chemistry at Colorado State University. Befor
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509: Studying Social Behavior, Reproduction, and Health in Female-Dominant Species - Dr. Christine Drea
08/07/2019 Duración: 41minDr. Christine Drea is the Earl D. McLean Professor of Evolutionary Anthropology, as well as Professor in the Department of Biology, the University Program in Ecology, and the Duke Institute for Brain Sciences at Duke University. Research in Christine’s lab examines animal behavior from an integrative perspective. She and her colleagues are investigating the genetic, behavioral, cognitive, sensory, and endocrine mechanisms involved in social interactions and communication in socially complex animals. Christine focuses primarily on female-dominant species such as hyenas, lemurs, and meerkats. Christine’s hobbies outside of science include gardening, playing and walking with her two dogs, and traveling. Christine completed her undergraduate training in zoology at the University of Maryland College Park. She earned her M.A. and Ph.D. degrees in psychobiology from Emory University. Afterwards, Christine conducted postdoctoral research in physiology at the Morehouse School of Medicine, and subsequently she was awar
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508: Investigating Genetic Profiles and Phenotypes of People with Parkinson's Disease - Dr. Paul Cannon
01/07/2019 Duración: 37minDr. Paul Cannon is the Parkinson’s Disease Program Manager at 23andMe. Paul and the team at 23andMe are working with patients, genetic data, and other self-report data to understand genetic mutations linked to Parkinson’s disease, disease risk factors, and other comorbidities experienced by people with Parkinson’s disease. Outside of work, Paul enjoys traveling to visit new places in countries or parts of countries that are not necessarily considered typical tourist destinations. He also likes to hike, watch cricket matches, and watch Premier League Soccer games. Paul received his Master’s degree in Natural Sciences from Christ’s College in Cambridge and his PhD in Medical Sciences from the University of Calgary. Afterwards, he worked as a Research Scientist at Syntex. Next, Paul spent nearly 15 years in various roles at Roche Pharmaceuticals and Genentech. He worked as a Senior Consultant for Tynan Consulting for about four years before joining the team at 23andMe. In our interview, Paul tells us more about
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507: Investigating How Frogs are Impacted by Climate Change, Fungal Disease, and Selection Pressures - Dr. Cori Richards-Zawacki
24/06/2019 Duración: 43minDr. Cori Richards-Zawacki is an Associate Professor in the Department of Biological Sciences and Director of the Pymatuning Lab of Ecology at the University of Pittsburgh. Cori studies topics in ecology, evolutionary biology, behavior, and conservation in frogs. In particular, she is working to understand how frogs use different body forms, colors, and other features to survive partially on land and partially in water. When she’s not working and doing research, Cori enjoys spending time outside with her husband and two young daughters. She likes to play soccer, hike, go mountain biking, and do other outdoor activities. Cori received her Bachelor’s degree in engineering and biology as well as her PhD in ecology and evolutionary biology both from the University of Michigan. She conducted postdoctoral research at the Smithsonian Institute and the University of California, Berkeley. Cori next served on the faculty at Tulane University prior to joining the faculty at the University of Pittsburgh in 2015. In our in
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506: Sage Scientist Developing New Drugs for Depression and Other Neurological Diseases - Dr. Jim Doherty
17/06/2019 Duración: 34minDr. Jim Doherty is Chief Research Officer at Sage Therapeutics, a clinical-stage biopharmaceutical company committed to developing and commercializing novel medicines to treat life-altering central nervous system disorders. Jim and his colleagues are focused on developing new treatments for different brain disorders including psychiatric, neurodegenerative, and movement disorders. Outside of science, Jim enjoys traveling, seeing cool new sites, and exploring the history of different places with his wife and two kids. He also enjoys participating in a variety of team sports like golf, softball, and ultimate frisbee leagues. Jim received his B.A. in biology from the University of Delaware and his Ph.D. in neuroscience from Georgetown University. Next, he conducted postdoctoral research at Emory University Medical School and subsequently served on the faculty at Emory for about two years. Prior to joining the team at Sage in 2014, Jim worked for about eleven years at AstraZeneca Pharmaceuticals. In our interview
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505: Developing Drugs to Treat Lupus Nephritis and Other Rare Diseases - Dr. Neil Solomons
10/06/2019 Duración: 24minDr. Neil Solomons is Chief Medical Officer and Co-Founder of Aurinia Pharmaceuticals, a clinical stage biopharmaceutical company focused on developing and commercializing therapies in disease areas of high unmet medical need. Neil is working to develop a drug to treat a rare autoimmune disease called lupus nephritis. In lupus nephritis, there is inflammation of the kidneys that can result in kidney failure, need for dialysis, or kidney transplant. Currently, there are no FDA-approved therapies for this disease, and the team at Aurinia is excited to be in the final stages of developing a drug called Voclosporin to treat lupus nephritis. Outside of research, Neil is an obsessive soccer fan, and he has been avidly watching English Premier League games since he was a child. He also enjoys playing the guitar and spending time with his family. Neil was awarded his Medical Degree from the University of London’s Guys Hospital Medical School. Afterwards, he worked as a physician in London and completed specialist trai