People Behind The Science Podcast - Stories From Scientists About Science, Life, Research, And Science Careers

Dr. Ryan Potts is VP of Research and Head of the Induced Proximity Platform at Amgen that works on ways to bring two or more molecules in close proximity to each other to tackle drug targets that are currently considered “undruggable.” Ryan conducts early-stage research to discover new high-impact medicines for serious diseases that have a high unmet medical need. Their work examines biological pathways, drug targets, disease drivers, and new ways to create drugs that have the desired effects. He also leads Amgen’s Research & Development Postdoctoral Fellows Program. Outside of science, Ryan enjoys spending quality time with his family and his kids. They enjoy exploring the natural world, hiking, and exploring the nearby Santa Monica Mountains and local beaches. Ryan is also an avid traveler and sports fan. Ryan received his BS in biology from the University of North Carolina at Chapel Hill, and he was awarded his PhD in cellular and molecular biology from UT Southwestern Medical Center. After completing

Dr. Pankaj Karande is an Associate Professor in Chemical and Biological Engineering at Rensselaer Polytechnic Institute. Pankaj was trained as a chemical engineer, and his research aims to apply engineering approaches and technology to solve problems in biology and healthcare to improve the quality and quantity of human life. Projects in his lab span areas such as drug discovery, drug delivery, biomaterials, diagnostics, and more. When he’s not working, Pankaj loves to cook, and experimenting with different recipes has been a great way to relieve stress. He was awarded his B.S. in Chemical Engineering from Mumbai University Institute of Chemical Technology and his Ph.D. in Chemical Engineering from the University of California, Santa Barbara. Pankaj was awarded an Anna Fuller Postdoctoral Fellowship in Molecular Oncology, and he conducted postdoctoral research in the Center for Cancer Research at Massachusetts Institute of Technology before joining the faculty at Rensselaer. Pankaj has received a variety of a

Dr. Claire Higgins is a Reader (faculty) in Tissue Engineering and Regenerative Medicine in the Department of Bioengineering at Imperial College London. She is also President of the European Hair Research Society and Vice President of the Institute of Trichologists, a professional association for researchers who study the hair and scalp. Claire teaches and conducts research in the areas of tissue engineering and regenerative medicine. She uses skin and hair follicles as models to better understand how tissues respond to injury, heal wounds, and repair after disease. Outside of science, making pottery has been one of Claire’s favorite pastimes since she took her first classes as a postdoc. She enjoys making items like bowls, vases, and lamp bases on her pottery wheel in her studio during her free time. Claire received her B.Sc. in natural sciences and her PhD in skin developmental biology from Durham University in England. Afterwards, she conducted postdoctoral research at Columbia University. She worked as an

Dr. Ariel Furst is the Paul M. Cook Career Development Professor in the Department of Chemical Engineering at Massachusetts Institute of Technology (MIT). In her research, Ariel has been using microbes to address problems surrounding human health, environmental remediation, and sustainability. Her lab focuses on energy equity by developing  new technologies that are accessible to people who haven’t had access to technology but are negatively impacted by it. She is also working towards energy justice by developing technology and approaches to remediate prior harms to marginalized communities. In her free time, Ariel and her husband enjoy experimenting with new recipes in the kitchen. She also likes to spend time outdoors hiking, jogging, and doing fun activities like apple picking with her lab members. She received her B.S. degree in chemistry from the University of Chicago and her PhD in chemistry from the California Institute of Technology. Afterwards, she was awarded a Beckman Foundation Postdoctoral Fellow

Dr. Michael Demetriou is Director of the National Multiple Sclerosis Society Designated Comprehensive Care Clinic, Professor of Neurology, and Chief of the Division of Multiple Sclerosis and Neuroimmunology at the University of California, Irvine (UCI) School of Medicine. In his research, Mike studies the biological roles of complex sugars called glycans. Glycans are mostly found outside of cells and on cell surfaces. They form a dense forest around the surface of cells and can interact with other proteins to regulate cellular function through interactions with other cell surface proteins. Mike’s lab is interested in how these cell surface glycans influence biology and disease, particularly in autoimmune diseases like multiple sclerosis (MS) and in diseases like cancer where there are commonly abnormalities in these glycans. Mike is also a big fan of the Toronto Maple Leafs hockey team. While he doesn’t play hockey himself anymore, he loves watching professional hockey games and seeing the Maple Leafs play wh

Dr. Beth Weaver is a Professor in the Department of Cell and Regenerative Biology and the Department of Oncology/McArdle Laboratory for Cancer Research at the University of Wisconsin-Madison School of Medicine and Public Health. She is co-Leader of the Developmental Therapeutics Program at the University of Wisconsin Carbone Cancer Center. Beth studies a group of commonly used chemotherapy agents to better understand how they work, who will respond to these treatments, and how to make resistant tumors more sensitive to these drugs. Outside of work, Beth enjoys spending time with her family. She, her husband, and their two children enjoy making fun group Halloween costumes, and she also brings this creativity into entertaining and hosting themed parties. Beth received her B.S. in biochemistry from Brown University and her Ph.D. in biomedical sciences from the University of California, San Diego. Afterwards, Beth conducted postdoctoral research at the Ludwig Institute for Cancer Research before joining the facu

Dr. Magdalena Osburn is an Associate Professor in the Department of Earth and Planetary Sciences at Northwestern University. Maggie's research brings together microbiology and geology to understand biological activity in different environments in the past and present. She studies unique microbes that live in extreme environments like deep mines, hot springs, and caves. When she’s not working, Maggie likes to go hiking, backpacking, and generally be outside exploring nature. When she’s able to get away, she loves going on road trips to enjoy the splendor of the mountains in Montana. At home, Maggie also spends her time doing yoga, running, and knitting. She received her bachelor’s degree in Earth & Planetary Sciences and Environmental Studies from Washington University in St. Louis. Afterwards, she enrolled in graduate school at the California Institute of Technology where she earned her M.S. and Ph.D. degrees in geobiology from the Division of Geological and Planetary Sciences. Next, Maggie conducted post

Dr. Erdem Tabdanov is Assistant Professor in the Department of Pharmacology at Penn State College of Medicine and also a Member of the Penn State Cancer Institute. He studies the mechanical and structural aspects of cells to better understand how cells physically move, sense their environments, and accomplish their various functions. This is very relevant to cancer biology and understanding the immune system. Some of Erdem’s hobbies outside of science include working out at the gym, calligraphy, sketching, digital art, and other visual arts. He is also considering adopting a cat. His interest in digital art emerged from his desire to put the story of his research together in compelling figures and schematics for journal articles. He received his bachelor’s degree in biotechnology and his MSc in chemistry and molecular and cellular biotechnology from Lomonosov Moscow State Academy of Fine Chemical Technology (MITHT). He was awarded his PhD in cancer research from L'Institut Curie in Paris. Afterwards, Erdem co

Dr. Alexis “Lekki” Wood is Associate Professor at USDA/ARS Children's Nutrition Research Center in the Division of Pediatrics-Nutrition at Baylor College of Medicine. Research in Lekki’s lab aims to better understand how food influences our health. She examines the full chain of changes that occur from the moment food is put into our mouths, trough digestion and absorption of particular molecules, to where those molecules go and how they affect our organs. Outside of work, you can find Lekki working out at the gym and spending quality time with her two children and their German shepherd. She is also a Lego builder and a competitive Pokemon card player along with her son. She received her BSc with honors in Psychology and from the University of Warwick. Afterwards, she completed her Postgraduate Certificate in Education at the University of Cambridge. Lekki enrolled in graduate school at King’s College London where she earned her MSc in social, genetic, and developmental psychiatry and her PhD in statistical g

Dr. Gareth Fraser is an Associate Professor in the Department of Biology at the University of Florida. Gareth is a developmental biologist interested in how things form during development, how they are recreated during regeneration, and how features develop and persist on evolutionary timescales. His lab typically examines these questions looking at oral teeth and dermal denticles (tooth-like structures) in unusual fish like pufferfish, hammerhead sharks, and ghost sharks (chimaera). When he’s not working, Gareth enjoys being outside in nature, playing soccer, scuba diving, and hunting for fossils in the creek near their home. He and his two young daughters have also been having fun exploring the mysterious realm of cryptozoology and reading books about monsters. Gareth received his bachelor’s degree in palaeobiology and evolution from the University of Portsmouth, his master’s degree in evolutionary biology and systematics from the University of Glasgow, and his PhD in evolutionary developmental biology from

Dr. Rachel Perry is Assistant Professor of Medicine (Endocrinology) and of Cellular and Molecular Physiology at the Yale University School of Medicine. Rachel’s scientific training focused on how our bodies use nutrients to stay healthy and what goes wrong in diseases like obesity and diabetes. In her current lab, she applies this background to better understand how changes in metabolism (nutrient supply) may affect cancer and how our bodies respond to cancer treatments. In her free time, Rachel enjoys spending time with her family, playing with their Labradoodle puppy, and going on walks in the fantastic fall weather. She is also an avid home chef, and she applies her scientific precision to prepare delicious meals for friends and family. She was awarded her B.S. in Biomedical Engineering and her Ph.D. (with Distinction) in Cellular & Molecular Physiology from Yale University. Afterwards, she remained at Yale for postdoctoral training in internal medicine and endocrinology, and she joined the Yale facult

Dr. Susie Dai is an Associate Professor in the Department of Plant Pathology and Microbiology at Texas A&M University. She is also Director of the Biomonitoring Program in the Iowa State Hygienic Laboratory, leading the Iowa Statewide Biomonitoring public health surveillance. Susie works at the interface of chemistry and biology, and her research leverages microorganisms like bacteria and fungus to synthesize chemicals of value or degrade poisonous chemicals. This work has important applications for developing sustainable methods to produce chemicals and breaking down dangerous chemicals that are very stable. In addition, Susie’s work also includes biomonitoring where they examine exposure to toxic chemicals from private wells and other environmental sources. When she’s not at work Susie enjoys reading and hanging out with her family, including her two wonderful daughters. Susie received her BS degree in Chemistry from Fudan University, and her PhD in Chemistry from Duke University. Afterwards, she conduc

Dr. Ralph Dewey is the Philip Morris Professor of Crop and Soil Sciences and Adjunct Professor of Plant and Microbial Biology at North Carolina State University (NCSU). Ralph uses the tools of molecular biology to identify and characterize genes of agronomic importance in crop species. When possible, he and his team alter those genes in ways that add value to the crop above and beyond what can be attained with traditional breeding approaches. Ralph and his team have done important work on the genetics of tobacco plants to decrease the hazards of smoking for people who still smoke. When Ralph has free time, he enjoys hanging out with his wife at their nearby beach condo and also watching college sports (particularly football and basketball). In addition, Ralph is working on writing his first novel. He was awarded his B.S. degree in biology from Utah State University, followed by his M.S. and Ph.D. in Crop Science from North Carolina State University. Afterwards, Ralph received an NSF Postdoctoral Research Fell

Dr. C. Denise Okafor is an Assistant Professor of Biochemistry and Molecular Biology, and of Chemistry at Pennsylvania State University. Many of the medications we take work by binding to a particular target and either turning off whatever is causing a problem or turning something on that is not working correctly. Denise’s research examines how small molecules like drugs find and interact with the targets they are supposed to interact with. She is particularly interested in proteins that can be turned on or off by the small molecules/drugs that they bind with. While science is a large part of Denise’s life, she also enjoys reading and writing fiction. Lately, she has been spending much of her free time with her kids, learning dances from Youtube videos and hanging out together. She received her B.S. in biomedical chemistry from Oral Roberts University and was awarded her M.S. in chemistry and a Ph.D. in biochemistry from Georgia Institute of Technology. Afterwards, Denise was selected to complete an Instituti

Dr. Laura Kiessling is the Novartis Professor of Chemistry at Massachusetts Institute of Technology (MIT) and Member of the Broad Institute. Laura’s research focuses on carbohydrates, particularly all of the different carbohydrates found on the surfaces of cells. We still know relatively little about the functions of these carbohydrates, and Laura is eager to learn more. When she’s not doing science, Laura likes being active through rowing, kayaking, cycling, lifting weights, or doing yoga. She also likes to spend her free time cooking, hiking, camping, and enjoying art. She received her BS degree in chemistry from MIT and her Ph.D. degree in organic chemistry from Yale University. After two years at the California Institute of Technology as an American Cancer Society Postdoctoral Fellow, she joined the faculty of the University of Wisconsin, Madison in 1991. She returned to MIT in 2017. Laura has received numerous awards over the course of her career, including the Ronald Breslow Award in Biomimetic Chemistr

Dr. Nicole Calakos is the Lincoln Financial Group Distinguished Professor of Neurobiology and Chief of the Movement Disorders section in Neurology at Duke University Medical Center. Research in Nicole’s lab examines how the brain learns and adapts to experiences. She studies synaptic plasticity, from the levels of molecules, cells, cell circuits, and behaviors, to understand what goes wrong in disease and how we can harness brain processes to address disease. When she’s not working, Nicole enjoys being outdoors, playing sports, running, going mountain biking, and participating in mountain bike races. Her favorite indoor activities include creative cooking and spending time with family and friends. Nicole was awarded her MD and PhD degrees from Stanford University. Afterwards, she completed an internship in Medicine and Residency in Neurology at the University of California, San Francisco School of Medicine. She conducted postdoctoral research at Stanford University before joining the faculty at Duke Universit

Dr. Alex Spyropoulos (“Dr. Spy”) is a Professor of Medicine at the Hofstra Northwell School of Medicine as well as System Director of Anticoagulation and Clinical Thrombosis Services for the multi-hospital Northwell Health System. In addition, Dr. Spy is a Professor of the Merinoff Center for Patient-Oriented Research as part of the Feinstein Institute for Medical Research. As a thrombologist, Dr. Spy studies blood clots. Many people worldwide are either at risk for blood clots or have existing clots. He focuses on venous thromboembolism primarily in the lungs and legs. These blood clots could cause morbidity or mortality, and many people are not familiar with the risks, common symptoms, or the situations in which clots may occur. Outside of work, Dr. Spy loves spending time with his wife and his young kids. Lately, they’ve been enjoying apple picking, hay rides, pumpkin carving, and apple carving. His other hobbies include sailing, snowboarding and mountain biking. He received his MD from the University of P

Dr. Erin Hodgson is an Associate Professor and Extension Entomologist at Iowa State University. She specializes in insects in agriculture, often focusing on corn and soybean crops. Erin also works with people like farmers, crop consultants, people in the agricultural industry, regulators, and people in pest management to best manage insect pests in an agricultural landscape. Erin spends her free time outside enjoying the company of her husband and two dogs. She is also an Assistant Coach for the Iowa State University Women’s Rugby Club and dedicates a lot of her time in the evenings to helping coach the team. She received her undergraduate training in Biology and Botany and her M.S. in Entomology from North Dakota State University. Erin was awarded her Ph.D. in Entomology from the University of Minnesota, followed by a postdoctoral research position also at the University of Minnesota. Erin served on the faculty at Utah State University before joining the faculty at Iowa State where she is today. Erin has rec

Dr. Sarah Bergbreiter is an Associate Professor in the Department of Mechanical Engineering with a joint appointment in the Institute for Systems Research at the University of Maryland. Sarah’s research involves building and conducting experiments with tiny locomoting robots that are about the size of ants. They also apply the same technologies used in their tiny robots to build better sensors and actuators for bigger robots to help improve performance of these robots. Spending time with her family is a big part of Sarah’s life outside of work. Her kids enjoy swimming, playing with legos, and building things. Sarah also spends her free time swimming and playing water polo. She received her B.S.E. degree in electrical engineering from Princeton University and was awarded her M.S. and Ph.D degrees in electrical engineering from the University of California at Berkeley where she focused on microrobotics. Sarah has been the recipient of multiple awards for her outstanding work including the DARPA Young Faculty Aw

Dr. Anand Padmanabhan is a pathologist, transfusion medicine physician, and Associate Professor of Laboratory Medicine and Pathology at the Mayo Clinic. Anand studies blood clotting, also known as “thrombosis”. He is working on a particular type of blood clotting that can occur when our bodies produce antibodies for proteins or other molecules inside or on the surface of blood platelets. Anand is interested both in finding better ways to diagnose and to treat patients with these potentially deadly diseases. When he’s not working, Anand loves spending time with his wife, their 15-year-old son, and their two dogs. They enjoy watching movies and traveling together across the U.S. and around the world. He received his Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.) degree from Thanjavur Medical College and completed a Clinical Internship in Medicine and Surgery at LLR and Associated Hospitals in India. He was awarded his PhD in biochemistry from Brown University. Afterwards, Anand completed his residency in