This Week In Virology With Vincent Racaniello

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Chari Cohen about her work as President of the Hepatitis B Foundation. Host: Rich Condit Guest: Chari Cohen Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Hepatitis B Foundation Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Committee of experts to counter vaccine misinformation (Science) NSF Director resigns (Science) Dependence of vaccine immune response on gut microbiome (Cell Host Microbe) Nucleosome switch primes HepB replication (Cell) Letters read on TWiV 1212 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Wild chimpanzees filmed by scientists bonding over alcoholic fruit Rich – Malcolm Gladwell Revisionist History “The Joe Rogan Intervention” Vincent – Measles Misinformation Is on the Rise — and Americans Are Hearing It, Survey Finds Intro music is by Ronald Jenkees Send your viro

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deplore the US’s withdrawal from the global health community for pandemic preparedness i.e. the universal avian flu vaccine, and undermining the use of routine childhood vaccinations for pertussis and measles, RFK’s autism registry, yellow fever outbreak in Colombia and world immunization week after discussing the squirrel as the reservoir host for mpox, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, how immunity elicited by the RSV vaccine wanes in 3 years, if Paxlovid reduces stroke, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, if vaccination impacts long COVID and if long COVID were to become epidemic. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The American Public’s Disengagement With High

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Stephan Urban about his career working on HBV and HDV, and his philanthropy. Host: Rich Condit Guest: Stephan Urban Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Hepatitis delta: recent advances (Hepatology) Bulevirtide for HBV and HDV (Lancet Inf Dis) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV discusses the rising autism rate among children, RFK Jr.’s claim that autism ‘destroys lives’, receptor binding specificity of a bovine H5N1 influenza virus, and improved dengue subunit vaccine modified to form E protein dimers. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Rising autism rate among children (MMWR) RFK Jr. claims autism ‘destroys lives‘ (NY Times) Receptor binding specificity of bovine H5N1 virus (Nature) Bovine H5N1 binds poorly to human receptors (Nature) AJ Eisfeld et al reply (Nature) Mootant influenza H5N1 virus (TWiV 1131) Improved dengue 2 subunit vaccine (J Virol) Letters read on TWiV 1211 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Scientists detect signature of life on a distant planet, study suggests Rich – Hanlon’s Razor Alan – Baby colossal squid filmed in deep ocean Vincent – How the United St

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Making America Healthy Again-purging of administrators at HHS (Politico) Maki

TWiV reviews RFK Jr’s odd comments on ‘single antigen’ vaccines and his September deadline for understanding why autism has increased, dire wolf does not come back from the dead, oral norovirus vaccine tablet that induces mucosal immunity in older adults, and identification of broadly neutralizing human monoclonal antibodies against norovirus. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 RFK Jr. and Novavax (MSN) September deadline to understand autism rise (Reuters) Dire wolf not resurrected (Science) Oral norovirus vaccine tablet (Sci Transl Med) Broadly neutralizing norovirus monoclonal antibodies (Sci Transl Med) Letters read on TWiV 1209 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – New experiment updates classic experiment on how life on Earth started Kathy – APOD ISS meets Venus, Sign up for NASA ISS alerts, GoISS Watc

In his weekly clinical update, Dr. Griffin with Vincent Racaniello mourn the demise of vaccination against childhood diseases when discussing the continuing measles outbreak and the rise of pertussis, the first human case of H5N1 in Mexico, and human metapneumovirus before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, if antiviral therapy prevents long COVID and how long COVID may affect brain volume. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode A natural experiment on the effect of herpes zoster vaccination on dementia (Nature) Taking a shot at dementia (microbeTV: TWiV) RFK Jr. visits Texas after second child dies of measles amid outbreak (Washington Post) Kennedy Att

TWiV notes the passing of Klaus Conzelmann, then reviews reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine, and reduction in dementia incidence in recipients of Zostavax. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Reverse zoonoses of 2009 H1N1 in US swine (PLoS Path) Zostavax reduces dementia (Nature) Letters read on TWiV 1207 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Rich – Certain Roller Coasters May Help Small Kidney Stones Pass Alan – Analog and Asimov’s science fiction magazines Vincent – Science Under Threat in the United States: How scientists and institutions should respond Listener Pick Charles – Why Techdirt Is Now A Democracy Blog (Whether We Like It Or Not)

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the continuing measles outbreak, whether or not the measles outbreak was predicted, the FACTS about vaccination, high pathogenic influenza, H5N1 contaminated raw pet food, children’s deaths, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and the efficacy of Moderna’s seasonal mRNA vaccine, societal burden of COVID-19 and influenza, the FDA missed deadline for approving Novovax COVID vaccine, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, and Canada’s long COVID dashboard. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC buried a measles forecast that stressed the need for vaccinations….TRANSPARENCY? (Politico) Measles cases and outbr

TWiV reviews liver damage caused by over use of vitamin A in Texas, vitamin A does not change clinical course of measles in high income country, NIH cuts COVID-19 research, US ends vaccine funds for poor countries, anti-vaxxer hired to study vaccines and autism, new DURC policy, Jamaican fruit bat competence for filoviruses, and human outbreaks of Oropouche virus reassortant in Brazil. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Vitamin A liver disease in Texas (NY Times) Vitamin A doesn’t help measles in high-income countries (Pediat Inf Dis) NIH cancels COVID grants (Science) US ends vaccine funds for poor countries (NY Times) Anti-vaxxer to study vaccines and autism (Sci Based Med) DURC rules revised (USG and NIH guidance) Filoviruses and Jamaican fruit bats (Nat Comm) Oropouche outbreaks in Brazil (Nat Med) Woolly mice (NPR) Letters re

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuing measles outbreak, the FACTS about vaccination, irresponsibility of promoting vitamin A therapy “lifelong liver damage or vaccinaton!”, high pathogenic influenza and egg importation before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and if vaccination affects long COVID, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, how to track long symptoms using a wearable device and how these data will never be used with the closing of governmental long COVID programs and offices. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles cases and outbreaks (CDC Rubeola) Measles 159 in Texas…. (Texas Health and Human Services) 2025 Measles ou

TWiV explains why RFK Jr.’s proposal to let H5N1 infections in birds ‘rip’ is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 RFK Jr. says let H5N1 rip through flocks (NY Times) Combined flu/COVID mRNA vaccine (Nat Comm) Rare syndrome after COVID vaccination (NY Times, medRxiv) Imprinting lasts 50 years (Immunity) Imprinting protects against H5N1 and H7N9 (Science) Letters read on TWiV 1203 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Node-Focal Plane Image Competition Rich – Periodic cooking of eggs Vincent – The use of placebo controls in clinical trials Listener Picks Anne – Everything is Tuberculosis by John Green Intro music is by Ronald Jenkees Send your v

In his weekly clinical update, Dr. Griffin and Vincent Racaniello rue about the unknowns of Sudan disease and new cases of paralytic polio, discuss the growing measles outbreak, exposure of newborns to measles, the FACTS about vaccination, high pathogenic influenza in dairy cows and cats, RFK’s statement “just let the virus rip through the hens” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and the relationship between EBV and long COVID. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode New cases of poliomyelitis  (GPEI) Polio in Africa (CIDRAP) Program for Monitoring Emerging Diseases (PROMED) ProMED Subscriptions (PROMED) Measles infected baby

Infectious diseases physician and author of ‘Booster Shots’ Adam Ratner joins TWiV to discuss measles, measles vaccination, how to approach anti-vaccine sentiment, and the uncertain future of children’s’ health. Hosts: Vincent Racaniello, Brianne Barker, and Jolene Ramsey Guest: Adam Ratner Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Booster Shots by Adam Ratner The Cutter Incident by Paul Offit Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello bemoan the continued outbreak of Sudan virus and growing number of paralytic polio cases before discussing growing measles outbreak in the US and Europe, the vaccine, an interview with a parent whose child died of measles infection, adverse effects of vaccination and how parents do not think they have accurate information about “bird flu” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and the benefits of antiviral therapies on post acute SARS-Cov-2 infection sequelae. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Sudan virus disease(WHO) New cases of poliomyelitis  (GPEI) Measle

TWiV covers a second death over 150 cases of measles in Texas, utter failure of removal of type 2 poliovirus from OPV, more OPV doses administered in Gaza, second Ebola outbreak in Sudan, vaccine being tested, Trump administration cancels $400 million in grants to Columbia University, bat-infecting merbecovirus that binds human ACE2 and infects human cells, and innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Second child dies of measles (NY Times) Over 150 measles cases in Texas (Texas DSHS) Utter failure of removal of OPV2 from OPV (Science) Over 600,000 doses of OPV administered in Gaza (polioeradication) Second outbreak of Sudan Ebola in Uganda (IAVI) Columbia grants canceled by administration (NBC News) Bat merbecovirus also infects human cells via Ace2 (Cel

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deliberate the effect of the absence of US foreign aid on the Ebola outbreak in Uganda and death of two children, continued use of nOPV2 in Gaza and the utter failure of type 2 poliovirus removal from the oral poliovirus vaccine, growing measles outbreak in the US including the death of a second child, measles infection parties, the use of fat soluble vitamin A and fish liver oil as anti-viral therapies as well as the history and proven safety of the measles vaccine before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions, long COVID interventions. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode African region: 

TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Ann Palmenberg dies (Cress) Ann at Chumakov Symposium (YouTube) Unknown illness in Congo (NY Times) Bad news about mpox outbreak (NPR) US interrupts Ebola prevention program (NPR) First measles death in Texas (Texas Trib) Flu vaccine selection meeting canceled (NY Times) US ends funding for polio, HIV, malaria and more (NY Times) Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio) Pre

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from “postponement” of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the ‘flu vaccine’ before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and growing measles outbreak in the US including misinformation from the Secretary of HHS, highly pathogenic avian flu and its economic effect, ie the cost of eggs before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and F