Dr. Ruscio Radio: Health, Nutrition And Functional Medicine

  • Autor: Vários
  • Narrador: Vários
  • Editor: Podcast
  • Duración: 594:40:51
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Sinopsis

Cutting edge information in health, nutrition and functional medicine distilled into practical advice you can use to improve your health.

Episodios

  • Gut Health Q&A: Akkermansia & Probiotic Misconceptions

    05/02/2024 Duración: 45min

    Tune in for an installment of my gut health Q&A, where I answer your questions about all things gut health. This installment is a probiotic edition, where I’ll touch on probiotic foods, dosing, side effects, and talk about whether the hype around Akkermansia is warranted. Be sure to tune in!  And if you have any questions you would like answered in a future installment, let me know in the comments!   Watch/Read Next… How Often to Take Probiotics and Other Probiotic Basics: https://drruscio.com/how-often-to-take-probiotics/  The Best Probiotic Protocol? The “Triple Therapy” Approach: https://drruscio.com/triple-therapy-probiotic-protocol/  A Review of Probiotic Research (2023): https://drruscio.com/probiotics-research-updates-2023/  SIBO, Probiotics, and Your Gut Health: A Long-Term Strategy: https://drruscio.com/sibo-probiotics/    Timestamps 00:00 Intro 01:27 Is Akkermansia hype warranted?  11:24 What are the best probiotics for IBS?  18:20 How long should I take probiotics?  22:00 Can probio

  • 8 Ways to Beat Brain Fog & Boost Your Cognition

    01/02/2024 Duración: 51min

    Here are 8 simple, practical ways to beat brain fog that you can start today.  Brain fog is the frustrating experience of cloudy, slowed thinking. Many of us have experienced it at some point, but if you’re struggling with it regularly, there’s a lot that you can do. Tune in!  And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… How to Get Rid of Brain Fog: Your Action Plan: https://drruscio.com/how-to-get-rid-of-brain-fog/  Brain Fog: A Research-Based Guide to Restoring Mental Clarity: https://drruscio.com/brain_fog/  Iron Deficiency Basics: https://drruscio.com/can-low-iron-cause-digestive-issues/  Vitamin B12 Deficiency More Common Than Thought: https://drruscio.com/vitamin-b12-deficiency-more-common-than-thought/  How to Boost Your Health with High Protein Snacks: https://drruscio.com/high-protein-snacks/  Chronic Fatigue with Dr. Jenny Tufenkian: https://drruscio.com/chronic-fatigue-and-viruses/    Timestamps 00:00

  • New Research to Resolve Constipation, Food Reactivity & Reflux

    29/01/2024 Duración: 33min

    The latest studies help inform how to resolve constipation, acid reflux, and food reactivity.  If you’re ready to nerd out about gut health, tune in.  And if you have any other gut health topics you’d like me to cover, let me know in the comments!   Watch/Read Next… Abdominal Self-Massage for Constipation: https://www.youtube.com/watch?v=zI4h_GXSJUk&t=2s   Get Your Gut Moving: Probiotics for Constipation: https://drruscio.com/probiotics-for-constipation/ Choosing the Best Natural Laxative for Your Gut Problem: https://drruscio.com/natural-laxatives/ From Bloating to Reflux: Resolving Gastrointestinal Symptoms: https://drruscio.com/gastrointestinal-symptoms/  How to Identify and Treat Laryngopharyngeal Reflux (LPR): https://drruscio.com/laryngopharyngeal-reflux/  How to Reduce Stress-Induced Inflammation in 5 Simple Steps: https://drruscio.com/reduce-stress-inflammation/  How Being in Nature Reduces Stress and Improves Your Health: https://drruscio.com/nature-reduces-stress/  Why You Have F

  • The 10 BEST Foods for Leaky Gut

    25/01/2024 Duración: 32min

    Leaky gut is COMMON. Finding the best foods for leaky gut can be confusing since much of the dietary advice is mixed.  Fortunately, extensive research has been conducted in this area and can show us exactly which foods are health-promoting for leaky gut. Tune in to hear the top 10 and how to get them in your diet. And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… A Step-by-Step Guide to the Low FODMAP Diet: https://drruscio.com/low-fodmap-diet/  Low FODMAP App: https://www.monashfodmap.com/ibs-central/i-have-ibs/get-the-app/  Low FODMAP Diet Guide Download: https://drruscio.com/getlowfodmapguide/  How to Drink Bone Broth: https://drruscio.com/how-to-drink-bone-broth/  Can You Get Enough Probiotics From Foods: https://www.youtube.com/watch?v=cFs9JRMg7eI    Timestamps 00:00 Intro  01:36 Turmeric  05:14 Clove & Peppermint  07:04 Dark Chocolate & Berries  11:19 Low FODMAPs 14:59 Bone broth 17:10 Kefir  18:14 Kimchi 1

  • The Science of Leaky Gut with Dr Michael Camilleri MD (Mayo Clinic)

    22/01/2024 Duración: 01h23min

    There’s still a lot we don’t understand about the science of leaky gut. Does it cause disease or is it a symptom? What’s the best way to test for it? Which treatments actually work to repair it?  Today’s guest is one of the best people to begin to answer these questions.  Dr. Camilleri is a renowned gastroenterology researcher and professor at the Mayo Clinic.  Tune in to hear about cutting-edge innovations and informed understandings around leaky gut testing and treatment.  If you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… What is Leaky Gut: https://drruscio.com/what-is-leaky-gut/  Leaky Gut Suplements: https://drruscio.com/leaky-gut-supplements/  Probiotics for Stomach Issues: https://drruscio.com/probiotics-for-stomach  Learn more about Dr. Camilleri’s work: https://www.mayo.edu/research/faculty/camilleri-michael-m-d-d-sc/bio-00026245    Timestamps 00:00 Intro  03:25 Dr. Camilleri’s background with leaky gut 05:05 Bile-aci

  • Probiotics Improve Leaky Gut, IBS & Candida [New Studies]

    18/01/2024 Duración: 31min

    New research doesn’t just tell us that probiotics improve leaky gut, candida, and IBS, it tells us how.  Join me to unpack the exciting findings behind probiotics for leaky gut, candida, and IBS, and a protocol you can use at home to help find relief.  And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… Create a Leaky Gut Diet Plan: https://drruscio.com/?p=56263  How to Spot Leaky Gut: https://www.youtube.com/watch?v=7QER7XXJ5CM&t=3s What’s the Strongest Candida Killer?: https://drruscio.com/strongest-candida-killer/  What is IBS? https://drruscio.com/what-is-ibs  How to Relieve the Symptoms of IBS Attacks: https://drruscio.com/stop-the-struggle-how-to-relieve-the-symptoms-of-ibs-attacks/    Timestamps 00:00 Intro  01:58 Impressive vaginal candida effectiveness  04:51 Gastrointestinal candida findings  05:56 Remarkable leaky gut results  10:04 Positive impacts to IBS symptoms  18:04 Where probiotics made no difference

  • What Is Berberine & Will It Actually Make You Lose Weight?

    15/01/2024 Duración: 17min

    You might have heard the buzz around berberine, often referred to as “nature's Ozempic”.   Berberine is a powerhouse for many things, from reducing inflammation to regulating blood sugar levels. Tune in to hear which benefits the science supports (and the surprising ones it doesn’t) and get a simple dosing guide.  And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… Diets Debunked: The Noom Program: https://drruscio.com/noom-debunked/  Diets Debunked: Weight Watchers: https://drruscio.com/weight-watchers/  Genetic Testing for Weight Loss Isn’t Worth it. Here’s what is: https://drruscio.com/genetic-testing-for-weight-loss/  How to Heal Your Gut Naturally: https://drruscio.com/how-to-heal-your-gut-naturally/     Timestamps 00:00 Intro  01:00 What is berberine?  01:37 Weight loss 02:34 Cholesterol 05:52 Blood sugar  08:47 Gut health  11:15 SIBO  12:53 Berberine dosing guide    Featured Studies  Biological properties and clinic

  • Probiotics Improve Immune System, Food Allergy & Stress

    08/01/2024 Duración: 30min

    Recent research highlights that probiotics can make a significant impact on a wide range of conditions like immunity, stress, allergies, and even lactose intolerance.  Tune in to hear the latest updates and stay in step with the science.   Read & Watch Next What is Leaky Gut? https://drruscio.com/what-is-leaky-gut/  How to Use Probiotics for Bloating & Constipation Relief: https://drruscio.com/probiotics-for-bloating/   How Long Does it Take for Probiotics to Work? https://drruscio.com/how-long-does-it-take-for-probiotics-to-work/  7 Surprising Things That are Stressing Your Nervous System: https://drruscio.com/things-stressing-your-nervous-system/  The Latest Research Update Episodes: https://drruscio.com/research-updates/   Why You Have Food Intolerances & How to Improve Them: https://www.youtube.com/watch?v=y-LNHKlk5Oc&t=14s    Timestamps 00:00 Intro  00:56 Benefits for white blood cells 04:11 Benefits for diarrhea & sickness duration 08:13 Benefits for the stress respons

  • The Best SIBO Probiotic Protocol

    04/01/2024 Duración: 15min

    There’s a common misconception that you shouldn’t take probiotics for SIBO.   Where this comes from is the thought that adding bacteria to a bacterial overgrowth must be a bad idea.   But this overlooks how probiotics actually work AND the plethora of data we have on probiotics for SIBO.  So let’s dive in to see what all the data actually means.    Read/Watch Next The Ultimate 3-Step SIBO Treatment Guide: https://drruscio.com/sibo-treatments/  Your Guide to Choosing the Right SIBO Diet: https://drruscio.com/sibo-diet/  SIBO, Probiotics & Your Gut: A Long-Term Strategy: https://drruscio.com/sibo-probiotics/    Featured Studies  Prophylactic Saccharomyces boulardii versus nystatin for the prevention of fungal colonization and invasive fungal infection in premature infants: https://pubmed.ncbi.nlm.nih.gov/23703468/  Saccharomyces boulardii and infection due to Giardia lamblia: https://pubmed.ncbi.nlm.nih.gov/16798698/  Probiotic Saccharomyces boulardii in the Treatment of Small Intestinal Bacte

  • Why You Get Brain Fog & What To Do About It

    21/12/2023 Duración: 23min

    Slow thinking, trouble finding words, & poor memory are all signs of brain fog. But what IS brain fog, really?  Tune in to hear what brain fog is and what's actually causing it, so you can treat and prevent it effectively.   Watch/Read Next How to Get Rid of Brain Fog: Your Action Plan: https://drruscio.com/how-to-get-rid-of-brain-fog/  How to Target Neuroinflammation and Beat Brain Fog: https://drruscio.com/neuroinflammation/ The Hidden Reason You Have Brain Fog:  https://www.youtube.com/watch?v=Ze-tgmDUwNs    Timestamps 00:00 Intro  02:00 Lifestyle causes 08:10 Nutritional causes  12:38 Hormonal causes  15:56 Gut causes    Featured Studies  https://pubmed.ncbi.nlm.nih.gov/36600580/ https://pubmed.ncbi.nlm.nih.gov/29320671/ https://pubmed.ncbi.nlm.nih.gov/34890786/ https://pubmed.ncbi.nlm.nih.gov/30468135/ https://pubmed.ncbi.nlm.nih.gov/34858761/ https://pubmed.ncbi.nlm.nih.gov/34682909/ https://pubmed.ncbi.nlm.nih.gov/29628432/ https://pubmed.ncbi.nlm.nih.gov/24136970/ https:/

  • 8 Signs You Have Leaky Gut

    18/12/2023 Duración: 16min

    Leaky gut symptoms go far beyond digestion. Let’s look at the 8 tell-tale signs of leaky gut that you’re likely overlooking.  Watch/Read Next… What is Leaky Gut? https://drruscio.com/what-is-leaky-gut/  The Elemental Diet: An Effective Therapy for Gut Relief https://drruscio.com/elemental-diet/  The 4 Most Effective Leaky Gut Treatments: https://www.youtube.com/watch?v=MW1ezm3d0JQ&t=1092s    Timestamps 00:00 Intro  00:49 What leaky gut is & how it’s measured  03:08 The digestive symptoms  06:04 Body-wide (systemic) symptoms     Featured Studies  Association between increased intestinal permeability and disease: A systematic review: https://www.sciencedirect.com/science/article/abs/pii/S221295881730160X#:~:text=Results,and%2017%E2%80%9365%25%20respectively. Plasma and fecal zonulin are not altered by a high green leafy vegetable dietary intervention: secondary analysis of a randomized control crossover trial: https://pubmed.ncbi.nlm.nih.gov/35413837/ Specific Immunoglobulin E and G to Co

  • How To Treat SIBO Without Spending A Fortune

    14/12/2023 Duración: 24min

    If you use the right therapies at the right time, there’s an 85% resolution rate for SIBO.  I’ll share which SIBO treatments are effective and, most importantly, how and when to do them to get the best results.    Watch/Read Next… What is SIBO? https://www.youtube.com/watch?v=3OjefHfOx2I  Low FODMAP guides: https://drruscio.com/getlowfodmapguide/  Monash low  FODMAP app: https://www.monashfodmap.com/ibs-central/i-have-ibs/get-the-app/  Biota Clear 1A: https://store.drruscio.com/products/biota-clear-1a  Elemental Heal: https://bit.ly/48Y2vuk  My articles: https://drruscio.com/blog/ My book: https://drruscio.com/getgutbook/  Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources   Featured Studies  The Structure and Function of the Human Small Intestinal Microbiota: Current Understanding and Future Directions: https://pubmed.ncbi.nlm.nih.gov/31344510/ Epidemiology of small intestinal bacterial overgrowt

  • What Is Hashimoto’s + How To Prevent Hypothyroidism

    11/12/2023 Duración: 13min

    Hashimoto’s thyroiditis is an autoimmune condition that affects the thyroid. It isn’t the same as hypothyroidism, but it is connected to it. Learn what Hashimoto’s disease is and what you can do to help prevent it from potentially progressing into hypothyroidism.  Featured Studies  Our paper: https://pubmed.ncbi.nlm.nih.gov/35999903/ Our paper: https://pubmed.ncbi.nlm.nih.gov/36079838/  https://pubmed.ncbi.nlm.nih.gov/35743024/ https://pubmed.ncbi.nlm.nih.gov/3066320/ https://pubmed.ncbi.nlm.nih.gov/34766382/ https://pubmed.ncbi.nlm.nih.gov/28052092/ https://pubmed.ncbi.nlm.nih.gov/11836274/ https://pubmed.ncbi.nlm.nih.gov/760358/ https://pubmed.ncbi.nlm.nih.gov/14558922/ https://pubmed.ncbi.nlm.nih.gov/10779140/#:~:text=Ultrasonography%20(US)%20may%20demonstrate%20a,from%2019%25%20to%2095%25. https://pubmed.ncbi.nlm.nih.gov/18324487/ https://pubmed.ncbi.nlm.nih.gov/32743538/ https://pubmed.ncbi.nlm.nih.gov/20361146/ https://pubmed.ncbi.nlm.nih.gov/11836274/ https://pubmed.ncbi

  • Research Updates for Fiber, Prebiotics, & Diet | Dec 2023

    06/12/2023 Duración: 18min

    There are some really valuable research updates to gut health therapies. Today I'll break down and simplify the latest studies but, even more importantly, what they mean for your gut health.  Be sure to tune in to hear about updates for fiber, prebiotics, and gut-healthy diets.   Featured Studies   https://pubmed.ncbi.nlm.nih.gov/30949662/ https://pubmed.ncbi.nlm.nih.gov/36059088/ https://pubmed.ncbi.nlm.nih.gov/37168869/ https://pubmed.ncbi.nlm.nih.gov/36370419/ https://pubmed.ncbi.nlm.nih.gov/36786182/ https://pubmed.ncbi.nlm.nih.gov/37350810/ https://pubmed.ncbi.nlm.nih.gov/36136861/ https://pubmed.ncbi.nlm.nih.gov/35816465/ https://eprints.whiterose.ac.uk/133354/3/FINAL%20ACG%20IBS%20MONOGRAPH%20March%202018.%20V3.%20%20Submitted%20version%20with%20%20highlights.pdf https://pubmed.ncbi.nlm.nih.gov/17353499/ https://pubmed.ncbi.nlm.nih.gov/37517631/ https://pubmed.ncbi.nlm.nih.gov/37318580/ https://pubmed.ncbi.nlm.nih.gov/37375587/ https://pubmed.ncbi.nlm.nih.gov/29202473/ ht

  • Why You Have Food Intolerances & How to Improve Them

    04/12/2023 Duración: 24min

    Food allergies are an immune issue, food intolerance is a digestive issue—one that you can likely fix.  Today I'll cover why food reactivity happens in the first place, what the symptoms are, and the simple changes you can make to help improve your food intolerances and expand your diet.  Featured Studies  https://pubmed.ncbi.nlm.nih.gov/37371277/ https://pubmed.ncbi.nlm.nih.gov/30566481/ https://pubmed.ncbi.nlm.nih.gov/36733768/ https://pubmed.ncbi.nlm.nih.gov/29105784/ https://pubmed.ncbi.nlm.nih.gov/35565858/ https://pubmed.ncbi.nlm.nih.gov/33463542/ https://pubmed.ncbi.nlm.nih.gov/32983091/ https://pubmed.ncbi.nlm.nih.gov/34942583/ https://pubmed.ncbi.nlm.nih.gov/34496250/ https://pubmed.ncbi.nlm.nih.gov/28274108/ https://pubmed.ncbi.nlm.nih.gov/22835332/ https://pubmed.ncbi.nlm.nih.gov/32060130/ https://pubmed.ncbi.nlm.nih.gov/37375587/ https://pubmed.ncbi.nlm.nih.gov/34261437/ https://pubmed.ncbi.nlm.nih.gov/35766861/ https://pubmed.ncbi.nlm.nih.gov/36362745/ https://pu

  • The 10 WORST Foods for Leaky Gut

    29/11/2023 Duración: 27min

    The exact foods that trigger leaky gut are going to vary from person to person, but there are 10 common culprits you’ll want to keep an eye out for.  Some of these are pretty intuitive, some counter-intuitive, and some are controversial. So join me to see what the research suggests you keep an eye out for when it comes to offending foods for leaky gut.    Featured Studies  https://www.sciencedirect.com/science/article/abs/pii/S221295881730160X#:~:text=Results,and%2017%E2%80%9365%25%20respectively. https://pubmed.ncbi.nlm.nih.gov/36677677/ https://www.hsph.harvard.edu/nutritionsource/processed-foods/#:~:text=Unprocessed%20foods%20include%20the%20natural,nutritional%20content%20of%20the%20food. https://pubmed.ncbi.nlm.nih.gov/37206892/ https://pubmed.ncbi.nlm.nih.gov/34299233/ https://pubmed.ncbi.nlm.nih.gov/30782617/ https://pubmed.ncbi.nlm.nih.gov/22210577/ https://pubmed.ncbi.nlm.nih.gov/35892789/ https://pubmed.ncbi.nlm.nih.gov/33336247/ https://pubmed.ncbi.nlm.nih.gov/29904158/ htt

  • What is SIBO? Signs & Natural Treatment Options

    27/11/2023 Duración: 20min

    SIBO stands for "small intestinal bacterial overgrowth," but what does it actually mean for your health?  We'll cover what SIBO looks like, what it does to your health, and the simple, natural things you can do to improve it.   Featured Studies  https://pubmed.ncbi.nlm.nih.gov/31550680/ https://pubmed.ncbi.nlm.nih.gov/28134633/ https://pubmed.ncbi.nlm.nih.gov/9200287/ https://pubmed.ncbi.nlm.nih.gov/36294338/ https://pubmed.ncbi.nlm.nih.gov/37389240/ https://pubmed.ncbi.nlm.nih.gov/37389240/ https://pubmed.ncbi.nlm.nih.gov/29761234/ https://pubmed.ncbi.nlm.nih.gov/23957651/ https://pubmed.ncbi.nlm.nih.gov/36612414/ https://pubmed.ncbi.nlm.nih.gov/29915215/ https://pubmed.ncbi.nlm.nih.gov/37389240/ https://pubmed.ncbi.nlm.nih.gov/29374417/ https://www.ncbi.nlm.nih.gov/books/NBK546634/ https://pubmed.ncbi.nlm.nih.gov/28716079/ https://pubmed.ncbi.nlm.nih.gov/9200287/ https://pubmed.ncbi.nlm.nih.gov/24417613/ https://pubmed.ncbi.nlm.nih.gov/33029272/ https://pubmed.ncbi.nlm.ni

  • Gut Health Q&A: Constipation, Bloating, Eczema & Parasites

    22/11/2023 Duración: 35min

    If your gut health isn't where you want it to be, today's Q&A will likely be of use to you.  I'll be covering some great question submissions like:  -I’ve tried water, prunes, and fiber, and nothing works for my constipation. What should I do?  -My bloating and constipation are slowly getting better with your protocol, but are not resolved. What else can I do?  -I have eczema, rosacea, and loose stool. I was wondering if my skin symptoms could be caused by a gut imbalance?  To hear answers to these questions and more, please join me.    Featured Studies  https://pubmed.ncbi.nlm.nih.gov/35565722/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506578/ https://pubmed.ncbi.nlm.nih.gov/33670115/ https://pubmed.ncbi.nlm.nih.gov/18456568/ https://pubmed.ncbi.nlm.nih.gov/35978397/ https://pubmed.ncbi.nlm.nih.gov/31494971/ https://pubmed.ncbi.nlm.nih.gov/37168869/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778187/  Related Resources For Low FODMAP Diet Gudies: www.drruscio.com/getlowfodmapg

  • The 3 BEST Hashimoto’s Thyroiditis Treatments & 3 to Avoid

    20/11/2023 Duración: 30min

    Learn what works for Hashimoto's thyroiditis and what doesn't.  Today I'll walk you through 3 research-backed treatments for Hashimoto's, and the 3 treatments you can avoid.  Tune in.    Featured Studies  https://pubmed.ncbi.nlm.nih.gov/35999903/ https://pubmed.ncbi.nlm.nih.gov/36079838/ https://pubmed.ncbi.nlm.nih.gov/35743024/ https://pubmed.ncbi.nlm.nih.gov/11836274/ https://pubmed.ncbi.nlm.nih.gov/760358/ https://pubmed.ncbi.nlm.nih.gov/14558922/ https://pubmed.ncbi.nlm.nih.gov/10779140/#:~:text=Ultrasonography%20(US)%20may%20demonstrate%20a,from%2019%25%20to%2095%25. https://pubmed.ncbi.nlm.nih.gov/18324487/ https://academic.oup.com/jcem/article/84/2/561/2864306 https://pubmed.ncbi.nlm.nih.gov/28052092/ https://pubmed.ncbi.nlm.nih.gov/32805423/ https://pubmed.ncbi.nlm.nih.gov/20361146/#:~:text=Background%3A%20Anti%2Dthyroid%20peroxidase%20antibodies,positive%20titers%20of%20these%20antibodies. https://pubmed.ncbi.nlm.nih.gov/30078965/  https://pubmed.ncbi.nlm.nih.gov/3748937

  • How to BEST Navigate a Herxheimer Reaction (Die-Off)

    15/11/2023 Duración: 19min

    A Herxheimer reaction (aka die-off) is essentially when a new protocol makes you feel worse before you start to feel better.  This often gets confused with intolerance, which makes sense when gauging how a new protocol makes you feel. But to make sure you aren’t jumping ship on a protocol that may actually be working for you, it’s important to learn how to recognize the difference between die-off and intolerance.  Join me to learn how to best navigate Herxheimer symptoms and what you can do to manage them.    Featured Studies  https://pubmed.ncbi.nlm.nih.gov/32491752/#:~:text=It%20usually%20manifests%20as%20fever,and%20exacerbation%20of%20skin%20lesions.  https://pubmed.ncbi.nlm.nih.gov/23632012/ https://pubmed.ncbi.nlm.nih.gov/28078798/ https://pubmed.ncbi.nlm.nih.gov/21381407/ https://pubmed.ncbi.nlm.nih.gov/29508268/ https://pubmed.ncbi.nlm.nih.gov/29460487/ https://pubmed.ncbi.nlm.nih.gov/24891990/ https://pubmed.ncbi.nlm.nih.gov/32020750/  https://pubmed.ncbi.nlm.nih.gov/29493919/  h

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