Circulation On The Run

This week please join author Sheri Hartman and Associate Editor Jarett Berry as they discuss the article "Impacts of Reducing Sitting Time or Increasing Sit-to-Stand Transitions on Blood Pressure and Glucose Regulation in Postmenopausal Women: Three-Arm Randomized Controlled Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250825.890592

This week please join authors Eric Olson and Qianqian Ding, and Senior Guest Editor Gianluigi Condorelli as they discuss the article "Genomic Editing of a Pathogenic Sequence Variant in ACTA2 Rescues Multisystemic Smooth Muscle Dysfunction Syndrome in Mice." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250818.61174

This week please join author Joachim Skovbo and Associate Editor Brendan Everett as they discuss the article "Association of Statin Treatment and Dose With the Clinical Course of Small Abdominal Aortic Aneurysms in Men: A 5-Year Prospective Cohort Study From 2 Population-Based Screening Trials." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250812.716960

This week please join author Christian Ruff and Associate Editor Andrea Russo as they discuss the article "Abelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation on Antiplatelet Therapy: A Prespecified Analysis of the AZALEA-TIMI 71 Trial." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20250804.510827

This week please join author Boyoung Joung and Associate Editor Svati Shah as they discuss the article "Proteomic Signatures for Risk Prediction of Atrial Fibrillation." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250728.351486

This week please join author Marek Hozman and Associate Editor Andrea Russo as they discuss the Original Research Article "COOPERATIVE-PFA: A Three-Arm Randomized Controlled Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250721.6011

This week's podcast is dedicated to Circulation's fifth annual Disparities issue. First, please join Associate Editor Karol Watson and Guest Editor Nilay Shah as they discuss the article "Centering Diné (Navajo) Voices: Barriers, Facilitators, and Perceptions of Cardiac Care Among Patients With Heart Failure in Rural Navajo Nation" with corresponding author Lauren Eberly. Then, Associate Editor Mercedes Carnethon and Guest Editor Nilay Shah discuss the Frame of Reference article "Health Equity: Are We There Yet?" with author Clyde Yancy. Don't miss this important episode! For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250710.251438

This week please join guest author Adam Griesemer and Associate Editor and Digital Strategies Editor Maryjane Farr as they discuss the Review Article "Cardiac Xenotransplantation: Current State and Future Directions." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250707.102697

This week please join guest host Susmita Sahoo and author Huize Pan as they discuss the article "Atherosclerosis Is a Smooth Muscle Cell–Driven Tumor-Like Disease." Dr Pan and his coauthors are the recipients of the 2025 Joseph Loscalzo Award. This award recognizes the best basic/translational article published in Circulation in the preceding 12 months. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250629.645452

This week please join author Yuxiang Dai and Associate Editor Esther Lutgens as they discuss the article "Modified mRNA Treatment Restores Cardiac Function in Desmocollin-2–Deficient Mouse Models of Arrhythmogenic Right Ventricular Cardiomyopathy." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250623.661904

This week please join author Robert Clarke and Associate Editor Wendy Post as they discuss the article "Causal Relevance of Lp(a) for Coronary Heart Disease and Stroke Types in East Asian and European Ancestry Populations: A Mendelian Randomization Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250617.454324

This week please join author Nikolaus Marx as he discusses the article "Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250609.351110

This week please join author Brian Lindman and Executive Editor and Editorialist James de Lemos as they discuss the article "Cardiac Biomarkers in Patients With Asymptomatic Severe Aortic Stenosis: Analysis From the EARLY TAVR Trial" and the accompanying editorial "Biomarkers to Guide the Timing of Aortic Valve Replacement in Asymptomatic Aortic Stenosis: Where Do We Stand After Early TAVR?" For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250529.497472

This week please join author Varsha Tanguturi and Associate Editor Dharam Kumbhani as they discuss the article "Electronic Provider Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: A Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250528.505920

This week please join author André Zimerman and Associate Editor Amit Khera as they discuss the article "Intensive Lowering of LDL Cholesterol Levels With Evolocumab in Autoimmune or Inflammatory Diseases: An Analysis of the FOURIER Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250519.268826

This week please join author Milind Desai and Associate Editor Mark Link as they discuss the article "Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results From VALOR-HCM."  For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250512.476310

This week please join author Jarett Berry as well as Guest Editor and Editorialist Paul Thompson as they discuss the article "High-Volume Physical Activity and Clinical Coronary Artery Disease Outcomes: Findings From the Cooper Center Longitudinal Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250505.656863

This week please join author Bin Zhou and Associate Editor Zhao Wang as they discuss the article "Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250428.805646

This week please join author Signe Glargaard and Associate Editor Justin Ezekowitz as they discuss the article "A Randomized Controlled Trial of Thoracentesis in Acute Heart Failure." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250421.239148

This week please join author Emmanuel Stamatakis and Associate Editor Jarett Berry as they discuss the article "Dose Response of Incidental Physical Activity Against Cardiovascular Events and Mortality." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250414.213483